Advances in dissecting mosquito innate immune responses to arbovirus infection.

نویسندگان

  • Rennos Fragkoudis
  • Ghassem Attarzadeh-Yazdi
  • Anthony A Nash
  • John K Fazakerley
  • Alain Kohl
چکیده

Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

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عنوان ژورنال:
  • The Journal of general virology

دوره 90 Pt 9  شماره 

صفحات  -

تاریخ انتشار 2009